Manticore venom

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Manticore venom is the poison of the manticore. It is deadly, and kills the instant it reaches the heart. According to Qyburn, it can be thickened with sorcery to delay the effect.[1]

Recent Events

A Clash of Kings

Daenerys Targaryen is nearly killed by a stinging manticore, used as an assassin's weapon by a Sorrowful Man.[2]

A Storm of Swords

Prince Oberyn Martell stabs Ser Gregor Clegane multiple times with a spear coated in poison during Tyrion Lannister's trial by combat.[3]

Gregor is dying, with his flesh rotting and the wounds oozing pus. He screams constantly, has violent convulsions, and the veins in his arm are turning black. Grand Maester Pycelle is unable to determine the substance that could cause this, and cannot heal him despite his efforts. When he leeches Gregor, all the leeches die.[4] Pycelle tells Tywin Lannister that he does not believe the poison could be manticore venom, because of that poison's usual instantaneous effect.[1]

A Feast for Crows

In Dorne, Tyene Sand tells Prince Doran Martell that she knows the poison that her father Oberyn used, and there is none slower or more agonizing.[5]

Queen Regent Cersei Lannister has the former maester Qyburn examine Gregor. Qyburn reports that Gregor is slowly dying in exquisite agony; all of Gregor's veins have turned black, and the poison has eaten a hole in his side as large as a fist. He believes the poison was in fact manticore venom, but thickened somehow, most likely with a spell, to prolong the Mountain's death. Qyburn convinces Cersei to allow him to move Gregor to the black cells, where his screaming cannot be heard by the rest of the Red Keep, and study him there to gain useful knowledge of the sorcerous poison.[1]