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Nightshade is a poison. It is one of the more common poisons.

Recent Events

A Clash of Kings

Tyrion Lannister sees nightshade in Grand Maester Pycelle's collection of medicines and poisons.[1]

A Storm of Swords

During Tyrion Lannister's trial for the death of King Joffrey Baratheon, Grand Maester Pycelle claims that Tyrion stole a sample of nightshade as well as other drugs from Pycelle's collection.[2]