|Died||In 127 AC, at King's Landing|
Fire & Blood (mentioned)|
The Rogue Prince (mentioned)
Mellos was a Grand Maester during the reign of Viserys I Targaryen. He replaced Grand Maester Runciter in 112 AC. Mellos as Grandmaester was called a moderating voice while on the small council, always urging calm and compromise whenever issues arose between the Blacks and the Greens. King Viserys regarded Mellos as a trusted friend. He encouraged the match between Laenor Velaryon and Princess Rhaenyra Targaryen, despite the fact that Laenor was known not to be interested in women. He also counselled forgiveness for the king's brother, Prince Daemon Targaryen. 
In 120 AC, Mellos in his writings is the one that suggested that the fire at Harrenhal that killed Lord Lyonel Strong and his heir, Ser Harwin Strong was ordered by Viserys I Targaryen. Mellos implies that the king had come to accept the rumors that his grandchildren by his daughter, Rhaenyra were really bastards sired by Ser Harwin, thus he desired to keep the truth concealed and kill the man who had dishonored his daughter. 
When King Viserys I Targaryen fell and sliced his hand open on the Iron Throne, Mellos was unsuccessful in treating the laceration. Princess Rhaenyra flew her own maester, Gerardys, from Dragonstone to treat her father. Gerardys swiftly amputated two of the King's fingers, saving his life. 
Mellos passed away one night in 127 AC, collapsing while climbing the serpentine steps. Rhaenyra recommended that Gerardys take his place as Grand Maester. Queen Alicent, on the other hand, wanted Maester Alfador, who served House Hightower, named to the office. Beset from both sides, Viserys chose neither, reminding both his wife and daughter that the Citadel would decide who filled the office. Archmaester Orwyle, in the end, was selected by the conclave as the new Grand Maester.
Mellos's written accounts were used frequently by Archmaester Gyldayn in his own writings. Gyldan considered Mellos's frequent leechings to be less effective than Maester Gerardys's potions and tinctures.
What of it? I am not fond of fish, but when fish is served, I eat it.—Mellos on the match between Laenor and Rhaenyra