From A Wiki of Ice and Fire
Greyscale is a disease that can leave flesh stiff and dead and the skin cracked and flaking, mottled black and grey and stone-like to the touch. The tongue and lips turn to stone.
It generally affects children, especially in cold damp climates. The victims are disfigured but also rendered immune to the rarer fatal form and to the grey plague. The free folk consider people who survive greyscale unclean. Tyrion Lannister believes that Garin's Curse is only greyscale.
Maesters say its progress could be stayed by limes, mustard poultices, and scalding-hot baths. Septons insist that prayer, sacrifice and fasting are the cure. It is also colloquially believed that severing any affected appendages may stop the disease from spreading, but this treatment is not always effective.
Persons with Greyscale
- Princess Maegelle Targaryen, died of greyscale.
- Harlon Greyjoy, died of greyscale.
- Shireen Baratheon, survived a bout as an infant.
- Jon Connington
- Shrouded Lord
- Stone men
A Dance with Dragons
Under the Bridge of Dream the Shy Maid's crew are attacked by stone men. Tyrion Lannister falls into the Rhoyne but Jon Connington manages to pull him out of saving his life, but Jon becomes infected with greyscale in the process.